Bacterial infection

Syphilis testing at home

Yes. LabX tests for Syphilis on a urine or blood sample, starting at $149 with the At-Home STI Panel β€” 10-target urine PCR. Our urine STI panel includes a PCR test for Treponema pallidum DNA. Urine PCR can detect the organism during active infection, but it is not a substitute for blood testing (serology), which is the standard way to find past or latent syphilis. Our blood panels test for syphilis with an RPR screening test on a small-volume blood sample; if the screen is reactive, the laboratory runs a treponemal confirmation test on a second, different method before reporting.

What is Syphilis?

Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. It can also pass from a pregnant person to a baby. Syphilis develops in stages and can affect many parts of the body if untreated.

Symptoms

Early syphilis may cause a painless sore that is easy to miss, followed later by a rash or other symptoms that can fade on their own. Many people do not notice symptoms, so testing is important. If you have symptoms, see a licensed physician β€” a test result is not a diagnosis.

Why testing matters

Syphilis is treatable with medicine prescribed by a clinician, and early treatment prevents the complications of later stages. Partners also need evaluation.

How LabX tests for Syphilis

Our urine STI panel includes a PCR test for Treponema pallidum DNA. Urine PCR can detect the organism during active infection, but it is not a substitute for blood testing (serology), which is the standard way to find past or latent syphilis. Our blood panels test for syphilis with an RPR screening test on a small-volume blood sample; if the screen is reactive, the laboratory runs a treponemal confirmation test on a second, different method before reporting. Samples are tested at LabX Diagnostic Systems, a CLIA-certified, COLA-accredited laboratory in Tampa, Florida. Results are typically reported in 2–3 business days from receipt.

Timing

A very recent exposure may not show up yet on either test. If you were exposed in the last few weeks, or you want to know about past infection, a licensed physician can advise on blood testing now and again later.

Panels that include Syphilis

LabX STI panels do not include HIV testing. For an HIV test, ask your provider or visit gettested.cdc.gov.

If your result is reactive

A reactive result is not a diagnosis. For blood tests, the laboratory confirms a reactive screen on a second, different method before reporting it. If a result is reactive, contact a licensed clinician β€” this laboratory does not treat or prescribe β€” tell recent partners, and know that, like every clinical laboratory, LabX is required by law to report positive results for these notifiable infections to the state health department confidentially. If you are unwell, pregnant or in severe pain, seek care right away.

Common questions

Can I test for Syphilis at home?

Yes. LabX tests for Syphilis on a urine or blood sample, starting at $149 with the At-Home STI Panel β€” 10-target urine PCR. Our urine STI panel includes a PCR test for Treponema pallidum DNA. Urine PCR can detect the organism during active infection, but it is not a substitute for blood testing (serology), which is the standard way to find past or latent syphilis. Our blood panels test for syphilis with an RPR screening test on a small-volume blood sample; if the screen is reactive, the laboratory runs a treponemal confirmation test on a second, different method before reporting.

Does Syphilis always cause symptoms?

Early syphilis may cause a painless sore that is easy to miss, followed later by a rash or other symptoms that can fade on their own. Many people do not notice symptoms, so testing is important.

What sample does the Syphilis test use?

Our urine STI panel includes a PCR test for Treponema pallidum DNA. Urine PCR can detect the organism during active infection, but it is not a substitute for blood testing (serology), which is the standard way to find past or latent syphilis. Our blood panels test for syphilis with an RPR screening test on a small-volume blood sample; if the screen is reactive, the laboratory runs a treponemal confirmation test on a second, different method before reporting.

What if my Syphilis result is positive or reactive?

A reactive result is not a diagnosis. For blood tests, the laboratory confirms a reactive screen on a second, different method before reporting it. If a result is reactive, contact a licensed clinician β€” this laboratory does not treat or prescribe β€” tell recent partners, and know that, like every clinical laboratory, LabX is required by law to report positive results for these notifiable infections to the state health department confidentially. If you are unwell, pregnant or in severe pain, seek care right away.

Should I test again later?

A very recent exposure may not show up yet on either test. If you were exposed in the last few weeks, or you want to know about past infection, a licensed physician can advise on blood testing now and again later.

Related infections

Terms: NAAT Β· reactive result Β· window period Β· notifiable condition. More: all STI tests Β· LabX answers.

Order a panel that tests for Syphilis

At-home drug tests and test kits are not currently available to addresses in New York, New Jersey, Rhode Island or California. Results are not a diagnosis β€” review them with a licensed physician.

At-Home STI Panel β€” 10-target urine PCR β€” $149 Blood STI Panel β€” Syphilis & Hepatitis β€” $199 Complete STI Panel β€” urine + blood β€” $299

Talk to a licensed physician. LabX Diagnostics and Vantage provide laboratory testing only. The information on this page is educational and is not medical advice, diagnosis or treatment. Always consult a licensed physician or other qualified healthcare provider about test results, symptoms or medicines, and before making any health decision. If you think you may have a medical emergency, call 911. Read our medical disclaimer.

Medical disclaimer. LabX Diagnostics and Vantage provide laboratory testing only. Test results and information on this site are for informational purposes and are not medical advice, diagnosis or treatment. Always consult a licensed physician or other qualified healthcare provider about your results and before making any health decision. If you think you may have a medical emergency, call 911. Read the full disclaimer.

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